At Sumitomo Chemical’s Agro & Life Solutions Research Laboratory in Takarazuka City, Hyogo Prefecture, researchers work on everything from agrochemicals, fertilizers, and agricultural materials—essential for growing safe, reliable crops and ensuring a stable food supply—to household insecticides. Their overarching themes are boosting crop yields and farm efficiency, and helping people live healthier, more hygienic lives. I was amazed to learn that this is where most of the active ingredients in the mosquito coils, liquid mosquito repellents, and aerosol insecticides we all know so well were actually developed. And in 2001, the World Health Organization (WHO) endorsed Olyset Net—a mosquito net with insecticidal ingredients incorporated in the fibers—as the world’s first long-lasting insecticidal net. The WHO now recommends its use in countries and regions struggling with malaria and other infectious diseases.
Agrochemicals and insecticides may be widely used already, but pests can develop resistance over time, making them less effective. And because people now expect products to be even safer and more environmentally friendly, the lab is continually taking on the challenge of creating new ones. What really surprised me was just how many years it takes for a single agrochemical to reach the world.
“First, we design and synthesize new compounds and ‘screen’ for promising candidates. We run initial tests in the lab and greenhouse to check the efficacy, safety, and environmental impact of the many compounds we produce, and if something looks good, we go as far as filing a patent. How long this stage takes really depends on the compound. From there, the development flow for an agrochemical goes through a ‘practicality assessment’ of the selected candidate, then—once we decide to move forward—into ‘development and registration filings,’ and finally ‘manufacturing and sales’ after the regulatory authorities complete their review,” explains Mr. Fujio Mukumoto, General Manager of the Research Planning & Coordination Office. “Even after a candidate is selected, it takes about 12 years on average, before it reaches the market.”
Mr. Mukumoto then took us through the labs and greenhouses where the preliminary evaluations and practicality assessments are carried out. “Here, we test the efficacy of candidate compounds for insecticides and fungicides by placing insects on pot-grown plants or inducing disease. To ensure accurate results, we grow the plants to uniform sizes and take care to keep out any insects other than the target pests,” he explains. Machines that automatically spray test compounds onto plants not only make the work more efficient but also help keep researchers safe.